Longevity & Cellular Health
PNC-27
PNC-27 — research-grade reference material, supplied in multiple sizes.
- Product Code
- PNC-27
- Purity
- 99%
- Form
- Lyophilized powder
- Packaging
- 10mg × 10 vials
Ships from multiple warehouses — typically 2–5 business days to nearby destinations. International orders coordinated per destination.
No prices are published. Available scope, specifications and documentation are confirmed during specification review. Supplied for research and analytical use by qualified organizations — see our Research Use Only policy.
Specification
- Purity specification
- 99%
- Appearance
- White to off-white lyophilized powder
- Solubility
- Reconstitutes in sterile or bacteriostatic water
- Counter ion
- Acetate
- Form
- Lyophilized Powder
- Available sizes
- 5mg × 10vials
- Storage
- Store lyophilized powder at -20°C, protected from light and moisture. After reconstitution, keep refrigerated at 2–8°C and use within the validated period.
- MOQ
- On request
Research Applications
- Research use: PNC-27, derived from the p53 C-terminal domain, is studied for its selective pro-apoptotic activity against tumor cells while sparing normal cells.
- Mechanistic studies focus on its interaction with MDM2 and the formation of lytic membrane pores on cancer cells as an apoptosis-independent killing mechanism.
- Used in cancer research as a tool to study peptide-based targeting of the p53/MDM2 axis and cancer cell membrane composition.
- Investigated for selective cytotoxicity against p53-overexpressing or p53-mutant tumor cell lines, informing peptide anticancer compound design.
p53 C-terminal derived peptide, selectively induces tumor cell apoptosis (research use)
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